Expect teh US to make a serious push for unmanned fighter interceptor aircraft. Given the early exposure to arcade games, kids today can react as well as pilots. In fact, they might be more daring, considering their life is not at stake.
However, the single greatest advantage of unmanned aircraft is maneuverability.
Humans black out when they push beyond Mach 9 (or so I've been told). Unmanned interceptors could conceivably pull 20+ Gs, outmaneuvering AAMs, SAMs, and enemy aircraft.
Expensive? Yeah.
Worth it? Only if you want to stay ahead of the pack by a generation or more.