Well I can't tell you how any of that relates to the Marines, but I have had severe depression since I was seven years old. (I'm 27 now)
So if you have any questions about depression in general I could answer them for ya... I know alot about it. And you don't nessesarily have to seem "sad" to be depressed. All the things you described:
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The symptoms mostly being poor memory, confusion, disappointment in self, trouble handling responsibilities.
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I don't blame your bro for wanting any meds.... Although if he doesn't mind herbal remedies St. Johns Wort is something to look into. If you have anything specific to ask me just PM me.